Compound Detail
CHEMBL3414912
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Basic Information
| ChEMBL ID | CHEMBL3414912 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKMBTSMUOCRZDS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
379.4
MW (Da)
3.05
ALogP
8
HBA
1
HBD
86.9
PSA (Ų)
0.52
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | IC50 | 7.28 | 7.28 | 52.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | IC50 | = | 52.0 | nM | 7.28 | Inhibition of recombinant c-Met kinase domain (unknown origin) incubated for 30 ... | 25699405 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25699405 | 10.1021/jm501913a | Liver microsome | 1 |
| 25699405 | 10.1021/jm501913a | Hepatocyte growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine