Compound Detail
CHEMBL3425612
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Basic Information
| ChEMBL ID | CHEMBL3425612 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KDFPHGIYWYFIAD-BJMVGYQFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
429.9
MW (Da)
5.49
ALogP
5
HBA
1
HBD
53.9
PSA (Ų)
0.42
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cell division protein FtsZ CHEMBL3999 | IC50 | 4.52 | 4.52 | 30000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cell division protein FtsZ | IC50 | = | 30000.0 | nM | 4.52 | Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupl... | 25815151 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25815151 | 10.1021/ml500497s | Cell division protein FtsZ | 1 |
Data from ChEMBL 36 via Core Engine