Compound Detail
CHEMBL3426977
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Basic Information
| ChEMBL ID | CHEMBL3426977 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RXGIBMQNACKGPV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
266.3
MW (Da)
3.28
ALogP
3
HBA
2
HBD
54.1
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.87
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| M-phase inducer phosphatase 2 CHEMBL4804 | IC50 | 4.87 | 4.87 | 13630.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| M-phase inducer phosphatase 2 | IC50 | = | 13630.0 | nM | 4.87 | Inhibition of His6-tagged human recombinant Cdc25B catalytic domain (350 to 566 ... | 25703307 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25703307 | 10.1016/j.bmc.2015.01.043 | M-phase inducer phosphatase 2 | 1 |
Data from ChEMBL 36 via Core Engine