Compound Detail
CHEMBL34907
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Basic Information
| ChEMBL ID | CHEMBL34907 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BUAPSNKVPWEGPA-VIFPVBQESA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
167.3
MW (Da)
1.49
ALogP
2
HBA
2
HBD
26.0
PSA (Ų)
0.66
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.41
Ki 1 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aminopeptidase N CHEMBL2590 | Ki | 7.52 | 7.52 | 30.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 7.41 | 7.41 | 39.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aminopeptidase N | Ki | = | 30.0 | nM | 7.52 | Inhibition of pig kidney Aminopeptidase N | 10386926 |
| Unchecked | IC50 | = | 39.0 | nM | 7.41 | Inhibition of partially purified soluble aminopeptidase from rat brain | 3184127 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3184127 | 10.1021/jm00119a023 | Unchecked | 1 |
| 10386926 | 10.1016/s0960-894x(99)00236-x | Aminopeptidase N | 1 |
Data from ChEMBL 36 via Core Engine