Compound Detail
CHEMBL352140
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Basic Information
| ChEMBL ID | CHEMBL352140 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KLJAXTVFYKOOCM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
220.3
MW (Da)
2.16
ALogP
3
HBA
1
HBD
24.5
PSA (Ų)
0.84
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B CHEMBL323 | Kd | 6.74 | 6.74 | 182.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B | Kd | = | 181.97 | nM | 6.74 | The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundus | 7086824 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7086824 | 10.1021/jm00343a013 | 5-hydroxytryptamine receptor 2B | 1 |
Data from ChEMBL 36 via Core Engine