Compound Detail
CHEMBL355307
PHENOSAFRANINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL355307 |
| Name | PHENOSAFRANINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GCJIBOGVEKFXNS-UHFFFAOYSA-O |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
287.4
MW (Da)
2.83
ALogP
3
HBA
2
HBD
68.8
PSA (Ų)
0.32
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | IC50 | 5.57 | 5.465 | 2700.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | IC50 | = | 2700.0 | nM | 5.57 | Tested for the binding of [3H]dizocilpine to DEPC (diethylpyrocarbonate) membran... | - |
| Glutamate NMDA receptor | IC50 | = | 4330.0 | nM | 5.36 | Tested for the binding of [3H]dizocilpine to NMDA receptor in rat brain membrane... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80097-9 | Glutamate NMDA receptor | 4 |
| - | 10.1016/S0960-894X(00)80097-9 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine