Compound Detail
CHEMBL355630
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Basic Information
| ChEMBL ID | CHEMBL355630 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DXCUBVVFKFOPGL-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
474.6
MW (Da)
6.04
ALogP
4
HBA
2
HBD
92.4
PSA (Ų)
0.33
QED
1
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 5.7 | 5.46 | 2000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 2000.0 | nM | 5.7 | Tested for inhibition of platelet aggregation induced by arachidonic acid (AAIPA... | - |
| Homo sapiens | IC50 | = | 6000.0 | nM | 5.22 | Tested for inhibition of platelet aggregation induced by U-46,619 (U-IPA) in hum... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80592-2 | Homo sapiens | 2 |
Data from ChEMBL 36 via Core Engine