Assay Detail
Functional
CHEMBL698303
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition of platelet aggregation induced by U-46,619 (U-IPA) in human platelet rich plasma
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Interphenylene phenyl oxazoles: novel, potent thromboxane receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.46 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31765 | — | — | 1 | 8.22 |
| CHEMBL170747 | — | — | 1 | 6.96 |
| CHEMBL355420 | — | — | 1 | 6.20 |
| CHEMBL366406 | — | — | 1 | 5.70 |
| CHEMBL355630 | — | — | 1 | 5.22 |
| CHEMBL171832 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31765 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL170747 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL355420 | — | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL366406 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL355630 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL171832 | — | IC50 | = | 330000.0 | nM | - |