Assay Detail
Functional
CHEMBL698304
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition of platelet aggregation induced by arachidonic acid (AAIPA) in human platelet rich plasma
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Interphenylene phenyl oxazoles: novel, potent thromboxane receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.61 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31765 | — | — | 1 | 8.70 |
| CHEMBL170747 | — | — | 1 | 7.51 |
| CHEMBL355420 | — | — | 1 | 7.24 |
| CHEMBL366406 | — | — | 1 | 6.33 |
| CHEMBL355630 | — | — | 1 | 5.70 |
| CHEMBL171832 | — | — | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31765 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL170747 | — | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL355420 | — | IC50 | = | 58.0 | nM | 7.24 |
| CHEMBL366406 | — | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL355630 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL171832 | — | IC50 | = | 67000.0 | nM | 4.17 |