Compound Detail
CHEMBL356597
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Basic Information
| ChEMBL ID | CHEMBL356597 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LMFAFFIRCNUJJO-OAHLLOKOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
420.2
MW (Da)
4.56
ALogP
3
HBA
1
HBD
72.2
PSA (Ų)
0.33
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(1A) dopamine receptor CHEMBL2056 | Ki | 7.55 | 7.55 | 28.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | Ki | = | 28.0 | nM | 7.55 | Ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 of canine str... | 2405157 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2405157 | 10.1021/jm00164a009 | D(1A) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine