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Compound Detail

CHEMBL3586014

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CC(=O)OCC1=C[C@H]2[C@@H]3C(C)(C)[C@]3(OC(C)=O)[C@H](OC(C)=O)[C@@H](C)[C@]2(O)[C@@H]2C=C(C)C(=O)[C@@]2(O)C1

Basic Information

ChEMBL ID CHEMBL3586014
Phase Preclinical
Structure Type MOL
InChI Key LASMKIAVFGUYEG-SEYWVDNQSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

490.6
MW (Da)
1.64
ALogP
9
HBA
2
HBD
136.4
PSA (Ų)
0.34
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C26H34O9
MW 490.55
Aromatic Rings 0
Heavy Atoms 35
NP-Likeness 2.97

Activity Summary

EC50 3 meas. best 5.18

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Human immunodeficiency virus 2
CHEMBL380
EC50 5.18 5.18 6600.0 1
Human immunodeficiency virus 1
CHEMBL378
EC50 4.56 4.56 27400.0 1
NON-PROTEIN TARGET
CHEMBL3879801
EC50 4.49 4.49 32600.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine