Compound Detail
CHEMBL35861
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL35861 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OZESMWJKGNPCBZ-ZICOIJLXSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
466.7
MW (Da)
6.56
ALogP
5
HBA
2
HBD
83.8
PSA (Ų)
0.14
QED
1
Ro5 Violations
18
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor CHEMBL2094254 | Ki | 6.0 | 6.0 | 1002.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor | Ki | = | 1002.0 | nM | 6.0 | Compound is evaluated for its ability to inhibit [3H]LTD4 binding to Cysteinyl l... | 3016267 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3016267 | 10.1021/jm00158a021 | Cysteinyl leukotriene receptor | 2 |
Data from ChEMBL 36 via Core Engine