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Compound Detail

CHEMBL358769

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OC[C@H]1O[C@@H](Oc2cc(O)cc(/C=C/c3ccc(O)c(O)c3)c2)[C@H](O)[C@@H](O)[C@@H]1O

Basic Information

ChEMBL ID CHEMBL358769
Phase Preclinical
Structure Type MOL
InChI Key PERPNFLGJXUDDW-CUYWLFDKSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names

Molecular Properties

406.4
MW (Da)
0.15
ALogP
9
HBA
7
HBD
160.1
PSA (Ų)
0.27
QED
1
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C20H22O9
MW 406.39
Aromatic Rings 2
Heavy Atoms 29
NP-Likeness 1.89

Activity Summary

IC50 3 meas. best 5.52

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
IC50 5.52 5.52 3000.0 1
Radical scavenging activity
CHEMBL613712
IC50 4.52 4.52 30200.0 1
Unchecked
CHEMBL612545
IC50 4.51 4.51 30600.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
20022753 10.1016/j.bmcl.2009.12.020 Streptococcus mutans 5
20022753 10.1016/j.bmcl.2009.12.020 Streptococcus sanguinis 5
29726680 10.1021/acs.jnatprod.7b00384 J774 3
14698182 10.1016/j.bmcl.2003.10.038 Unchecked 2
29402747 10.1016/j.bmcl.2018.01.063 Estrogen receptor 2
9599270 10.1021/np9704819 Radical scavenging activity 1
9599270 10.1021/np9704819 NON-PROTEIN TARGET 1
29726680 10.1021/acs.jnatprod.7b00384 Unchecked 1

Data from ChEMBL 36 via Core Engine