Compound Detail
CHEMBL359504
DISODIUM MALONATE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL359504 |
| Name | DISODIUM MALONATE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PRWXGRGLHYDWPS-UHFFFAOYSA-L |
2
Targets
7
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
148.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 7 meas. best 5.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Carbonic anhydrase 4 CHEMBL3729 | Ki | 5.55 | 5.55 | 2800.0 | 1 |
| Carbonic anhydrase CHEMBL5337 | Ki | 4.58 | 4.58 | 26300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 4 | Ki | = | 2800.0 | nM | 5.55 | Binding affinity against human cytosolic Carbonic anhydrase IV | 15664815 |
| Carbonic anhydrase | Ki | = | 26300.0 | nM | 4.58 | Inhibition of Candida albicans Nce103 | 19297172 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15664815 | 10.1016/j.bmcl.2004.11.057 | Carbonic anhydrase 1 | 1 |
| 15664815 | 10.1016/j.bmcl.2004.11.057 | Carbonic anhydrase 2 | 1 |
| 15664815 | 10.1016/j.bmcl.2004.11.057 | Carbonic anhydrase 4 | 1 |
| 15664815 | 10.1016/j.bmcl.2004.11.057 | Carbonic anhydrase 5A, mitochondrial | 1 |
| 15664815 | 10.1016/j.bmcl.2004.11.057 | Carbonic anhydrase 9 | 1 |
| 19297172 | 10.1016/j.bmc.2009.02.058 | Carbonic anhydrase 2 | 1 |
| 19297172 | 10.1016/j.bmc.2009.02.058 | Unchecked | 1 |
| 19297172 | 10.1016/j.bmc.2009.02.058 | Carbonic anhydrase | 1 |
Data from ChEMBL 36 via Core Engine