Compound Detail
CHEMBL363221
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL363221 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FVBRWQIUJUHLKQ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
269.4
MW (Da)
1.87
ALogP
3
HBA
2
HBD
76.2
PSA (Ų)
0.66
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | IC50 | 5.02 | 5.02 | 9600.0 | 1 |
| Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase CHEMBL1741212 | IC50 | 4.82 | 4.82 | 15000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | IC50 | = | 9600.0 | nM | 5.02 | In vitro inhibitory concentration against hepatitis C virus internal ribosome en... | 15380215 |
| Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | IC50 | = | 15000.0 | nM | 4.82 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS small molecule inhibitors o... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15380215 | 10.1016/j.bmcl.2004.07.066 | Hepatitis C virus | 2 |
| 24138284 | 10.1021/jm401312n | Internal ribosome entry site (IRES) | 1 |
Data from ChEMBL 36 via Core Engine