Compound Detail
CHEMBL363657
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Basic Information
| ChEMBL ID | CHEMBL363657 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UZCSGUXZTYSOQS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
276.2
MW (Da)
2.13
ALogP
5
HBA
1
HBD
94.6
PSA (Ų)
0.67
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HEK293 CHEMBL614818 | EC50 | 5.37 | 5.37 | 4243.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HEK293 | EC50 | = | 4243.0 | nM | 5.37 | PUBCHEM_BIOASSAY: PMA/Ionomycin induced NF-kB luciferase assay in 293- NF-kB-Luc... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15456272 | 10.1021/jm049972y | Vero | 2 |
| 15456272 | 10.1021/jm049972y | Mycobacterium tuberculosis | 1 |
| 15456272 | 10.1021/jm049972y | UDP-galactopyranose mutase | 1 |
| 15456272 | 10.1021/jm049972y | ADMET | 1 |
Data from ChEMBL 36 via Core Engine