Compound Detail
CHEMBL3655754
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC1(c2cc(Nc3nc(N4C[C@@H](O)C[C@H]4C(=O)Nc4cnccn4)nn4cccc34)[nH]n2)CC1
Basic Information
| ChEMBL ID | CHEMBL3655754 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ANZQPPMQRCSEJD-ZFWWWQNUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
460.5
MW (Da)
1.62
ALogP
10
HBA
4
HBD
149.2
PSA (Ų)
0.34
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Insulin-like growth factor 1 receptor CHEMBL1957 | IC50 | 8.7 | 8.7 | 2.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Insulin-like growth factor 1 receptor | IC50 | = | 2.0 | nM | 8.7 | Tyrosine Kinase Assay: Kinase assay using IGF1-receptor. | - |
Data from ChEMBL 36 via Core Engine