Compound Detail
CHEMBL3660643
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Basic Information
| ChEMBL ID | CHEMBL3660643 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OECYUCQGNLSDTE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
439.5
MW (Da)
3.85
ALogP
7
HBA
1
HBD
97.3
PSA (Ų)
0.62
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A CHEMBL6140 | IC50 | 9.43 | 9.43 | 0.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | IC50 | = | 0.369 | nM | 9.43 | Enzyme Inhibition Assay: An IMAP TR-FRET assay was used to analyze the enzyme ac... | - |
Data from ChEMBL 36 via Core Engine