Compound Detail
CHEMBL3666786
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Basic Information
| ChEMBL ID | CHEMBL3666786 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UPBJWRXHQFMCET-AULYBMBSSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
400.4
MW (Da)
2.92
ALogP
6
HBA
2
HBD
97.1
PSA (Ų)
0.74
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 9.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuropeptide Y receptor type 5 CHEMBL3802 | IC50 | 9.66 | 9.66 | 0.2 | 1 |
| Neuropeptide Y receptor type 5 CHEMBL4561 | IC50 | 9.07 | 9.07 | 0.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuropeptide Y receptor type 5 | IC50 | = | 0.22 | nM | 9.66 | Binding Assay: cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys.... | - |
| Neuropeptide Y receptor type 5 | IC50 | = | 0.86 | nM | 9.07 | Binding Assay: cDNA sequence encoding a human NPY Y5 receptor (WO96/16542) was c... | - |
Data from ChEMBL 36 via Core Engine