Compound Detail
CHEMBL366731
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL366731 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FSRMNBLCZIURKT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
471.9
MW (Da)
1.77
ALogP
7
HBA
2
HBD
138.2
PSA (Ų)
0.46
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Coagulation factor X CHEMBL244 | Ki | 8.52 | 8.52 | 3.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Coagulation factor X | Ki | = | 3.0 | nM | 8.52 | Inhibition of Coagulation factor Xa | 11958994 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11958994 | 10.1016/s0960-894x(02)00056-2 | Coagulation factor X | 1 |
| 11958994 | 10.1016/s0960-894x(02)00056-2 | Prothrombin | 1 |
| 11958994 | 10.1016/s0960-894x(02)00056-2 | Serine protease 1 | 1 |
| 11958994 | 10.1016/s0960-894x(02)00056-2 | Vitamin K-dependent protein C | 1 |
| 11958994 | 10.1016/s0960-894x(02)00056-2 | Plasminogen | 1 |
| 11958994 | 10.1016/s0960-894x(02)00056-2 | Tissue-type plasminogen activator | 1 |
Data from ChEMBL 36 via Core Engine