Compound Detail
CHEMBL3676251
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Basic Information
| ChEMBL ID | CHEMBL3676251 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DXSMZHHSVJSGHW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
338.4
MW (Da)
1.58
ALogP
7
HBA
1
HBD
89.6
PSA (Ų)
0.69
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 3',5'-cyclic-AMP phosphodiesterase 4A CHEMBL254 | IC50 | 6.58 | 6.58 | 261.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 3',5'-cyclic-AMP phosphodiesterase 4A | IC50 | = | 261.0 | nM | 6.58 | Binding Assay: Human recombinant PDE4 (Gene bank accession no NM006203) was incu... | - |
Data from ChEMBL 36 via Core Engine