Compound Detail
CHEMBL368456
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Basic Information
| ChEMBL ID | CHEMBL368456 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VDHWYWSLUYRNGE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
345.8
MW (Da)
3.63
ALogP
4
HBA
3
HBD
63.9
PSA (Ų)
0.59
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dopamine receptor CHEMBL2096905 | EC50 | 6.91 | 6.91 | 122.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dopamine receptor | EC50 | = | 122.0 | nM | 6.91 | Tested in vitro for dopamine agonist activity in rabbit ear artery after at a do... | 6306238 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6306238 | 10.1021/jm00361a001 | Canis familiaris | 6 |
| 6306238 | 10.1021/jm00361a001 | Dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine