Compound Detail
CHEMBL3696249
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Basic Information
| ChEMBL ID | CHEMBL3696249 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NTAOIWALWNRWCN-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
346.4
MW (Da)
1.24
ALogP
5
HBA
2
HBD
87.3
PSA (Ų)
0.87
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAC-alpha serine/threonine-protein kinase CHEMBL4282 | IC50 | 7.24 | 7.24 | 58.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAC-alpha serine/threonine-protein kinase | IC50 | = | 58.0 | nM | 7.24 | Inhibitory Assay: This test is based on measuring the expression of the AKT prot... | - |
| RAC-alpha serine/threonine-protein kinase | IC50 | = | 58.0 | nM | 7.24 | Inhibitory Assay: This test is based on measuring the expression of the AKT prot... | - |
Data from ChEMBL 36 via Core Engine