Compound Detail
CHEMBL3704013
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Basic Information
| ChEMBL ID | CHEMBL3704013 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PSNYRIOHVUOFPW-FLOSOGMCSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
447.6
MW (Da)
3.77
ALogP
9
HBA
1
HBD
82.2
PSA (Ų)
0.28
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | IC50 | 8.22 | 8.22 | 6.0 | 1 |
| Phosphodiesterase 3 CHEMBL2094125 | IC50 | 4.96 | 4.96 | 11000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | IC50 | = | 6.0 | nM | 8.22 | LanthaScreen Assay: The kinase assay is based on the LanthaScreen technology. La... | - |
| Phosphodiesterase 3 | IC50 | = | 11000.0 | nM | 4.96 | Scintillation Proximity Assay (SPA): The kinase assay is based on the LanthaScre... | - |
Data from ChEMBL 36 via Core Engine