Compound Detail
CHEMBL371561
ETHYLBENZENE Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL371561 |
| Name | ETHYLBENZENE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YNQLUTRBYVCPMQ-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
106.2
MW (Da)
2.25
ALogP
0
HBA
0
HBD
0.0
PSA (Ų)
0.51
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 3 meas. best 4.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Endolysin CHEMBL5206 | Kd | 4.36 | 4.2333 | 44000.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Endolysin | Kd | = | 44000.0 | nM | 4.36 | Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102E double mutant ex... | 23473072 |
| Endolysin | Kd | = | 68000.0 | nM | 4.17 | Dissociation constant against T4 lysozyme mutant L99A | 15916423 |
| Endolysin | Kd | = | 68000.0 | nM | 4.17 | Binding affinity to Enterobacteria phage T4 lysozyme L99A mutant expressed in Es... | 23473072 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23473072 | 10.1021/jm301823g | Endolysin | 4 |
| 894678 | 10.1021/jm00218a017 | No relevant target | 3 |
| 15916423 | 10.1021/jm0491187 | Endolysin | 1 |
| 19056282 | 10.1016/j.bmc.2008.11.040 | ADMET | 1 |
| 17629592 | 10.1016/j.ejmech.2007.05.007 | No relevant target | 1 |
| 1271397 | 10.1021/jm00227a001 | No relevant target | 1 |
| 1271417 | 10.1021/jm00227a031 | No relevant target | 1 |
| 915902 | 10.1021/jm00221a013 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine