Compound Detail
CHEMBL3763885
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3763885 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JPKCOYGPXKMZEL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
320.8
MW (Da)
3.35
ALogP
5
HBA
0
HBD
60.4
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HaCaT CHEMBL614392 | IC50 | 5.91 | 5.91 | 1220.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HaCaT | IC50 | = | 1220.0 | nM | 5.91 | Antihyperproliferative activity against human HaCaT cells after 48 hrs by phase ... | 26840368 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26840368 | 10.1016/j.ejmech.2016.01.040 | HaCaT | 2 |
Data from ChEMBL 36 via Core Engine