Compound Detail
CHEMBL376484
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C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CCSCC(=O)NC[C@H](N)C(=O)N[C@@H](Cc2ccc(N)cc2)C(=O)N[C@@H](CS)C(=O)N[C@H](CO)[C@@H](C)O)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O
Basic Information
| ChEMBL ID | CHEMBL376484 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WPMGOIJYJLHETB-HPFAXATKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1353.6
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor CHEMBL2111436 | IC50 | 9.3 | 9.3 | 0.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor | IC50 | = | 0.5 | nM | 9.3 | Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranes | 17315859 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17315859 | 10.1021/jm061290i | Somatostatin receptor | 1 |
Data from ChEMBL 36 via Core Engine