Compound Detail
CHEMBL377929
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL377929 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JGQHLETVKDCCET-NRIIQWGUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
318.5
MW (Da)
5.10
ALogP
2
HBA
0
HBD
6.5
PSA (Ų)
0.68
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Amyloid-beta precursor protein CHEMBL2487 | Ki | 6.08 | 6.08 | 837.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein | Ki | = | 837.0 | nM | 6.08 | Displacement of [125I]2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyridine fr... | 16640346 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16640346 | 10.1021/jm051020k | Amyloid-beta precursor protein | 2 |
Data from ChEMBL 36 via Core Engine