Compound Detail
CHEMBL3792736
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3792736 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UJBYRAUXLUMCGW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
458.4
MW (Da)
3.49
ALogP
9
HBA
3
HBD
145.6
PSA (Ų)
0.42
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | EC50 | 5.82 | 5.82 | 1500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | EC50 | = | 1500.0 | nM | 5.82 | Antiproliferative activity against human KMS11 expressing luciferase gene after ... | 26995528 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26995528 | 10.1016/j.bmcl.2016.03.037 | Liver microsome | 2 |
| 26995528 | 10.1016/j.bmcl.2016.03.037 | Serine/threonine-protein kinase pim-1 | 1 |
| 26995528 | 10.1016/j.bmcl.2016.03.037 | Serine/threonine-protein kinase pim-2 | 1 |
| 26995528 | 10.1016/j.bmcl.2016.03.037 | Serine/threonine-protein kinase pim-3 | 1 |
| 26995528 | 10.1016/j.bmcl.2016.03.037 | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine