Compound Detail
CHEMBL38084
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Basic Information
| ChEMBL ID | CHEMBL38084 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IEGJCGCABCXNEB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
470.6
MW (Da)
6.73
ALogP
5
HBA
2
HBD
77.4
PSA (Ų)
0.31
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 CHEMBL260 | IC50 | 6.96 | 6.96 | 110.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 | IC50 | = | 110.0 | nM | 6.96 | Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 | 12039561 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12039561 | 10.1016/s0960-894x(02)00238-x | Mitogen-activated protein kinase 14 | 1 |
Data from ChEMBL 36 via Core Engine