Compound Detail
CHEMBL382727
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Basic Information
| ChEMBL ID | CHEMBL382727 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BWEPEITXSAHIDR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
398.5
MW (Da)
5.61
ALogP
4
HBA
1
HBD
45.9
PSA (Ų)
0.45
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mus musculus CHEMBL375 | EC50 | 5.4 | 5.4 | 4020.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mus musculus | EC50 | = | 4020.0 | nM | 5.4 | Concentration required to inhibit dexamethasone-induced death of mice thymocytes | 16190767 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16190767 | 10.1021/jm0502034 | Mus musculus | 2 |
| 16190767 | 10.1021/jm0502034 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine