Compound Detail
CHEMBL387528
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Basic Information
| ChEMBL ID | CHEMBL387528 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MVKHEOPDKHNXGG-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
323.3
MW (Da)
3.42
ALogP
6
HBA
2
HBD
113.8
PSA (Ų)
0.32
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.7 | 4.7 | 20100.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 20100.0 | nM | 4.7 | Inhibition of yeast alpha glucosidase at pH 6.8 | 17331734 |
| Unchecked | IC50 | = | 20100.0 | nM | 4.7 | Inhibition of yeast alpha glucosidase in phosphate buffer after 0.5 hrs by spect... | 18632275 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18632275 | 10.1016/j.bmc.2008.06.043 | Unchecked | 2 |
| 17331734 | 10.1016/j.bmc.2007.02.030 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine