Compound Detail
CHEMBL388526
ANTICIN A Enter ChEMBL ID:
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C=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=C(C(=O)C[C@]12C)[C@@]1(C)CCC(=O)[C@@H](C)[C@@H]1CC3)[C@H](C)C(=O)O
Basic Information
| ChEMBL ID | CHEMBL388526 |
| Name | ANTICIN A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WTSUWKBKPMVEBO-QNMMDLTMSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
454.6
MW (Da)
6.40
ALogP
3
HBA
1
HBD
71.4
PSA (Ų)
0.47
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neutrophil CHEMBL613710 | IC50 | 5.07 | 5.07 | 8550.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neutrophil | IC50 | = | 8550.0 | nM | 5.07 | Inhibition of fMLP-induced superoxide production in human neutrophils | 17559265 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17559265 | 10.1021/np070045e | Neutrophil | 1 |
Data from ChEMBL 36 via Core Engine