Compound Detail
CHEMBL3893026
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3893026 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LTCCGKRFGBBEHR-UHFFFAOYSA-N |
3
Targets
6
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
356.3
MW (Da)
5.24
ALogP
2
HBA
1
HBD
40.5
PSA (Ų)
0.80
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 6 meas. best 7.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 4 CHEMBL2052036 | EC50 | 7.29 | 7.105 | 51.0 | 2 |
| Free fatty acid receptor 4 CHEMBL5339 | EC50 | 6.72 | 6.48 | 190.0 | 3 |
| Free fatty acid receptor 1 CHEMBL4422 | EC50 | 5.2 | 5.2 | 6300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 4 | EC50 | = | 51.0 | nM | 7.29 | Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as induction ... | 28105274 |
| Free fatty acid receptor 4 | EC50 | = | 120.0 | nM | 6.92 | Agonist activity at mouse GPR120 expressed in U2OS cells assessed as induction o... | 28105274 |
| Free fatty acid receptor 4 | EC50 | = | 190.0 | nM | 6.72 | Agonist activity at ARMS2-PK2 -tagged human GPR120 short isoform expressed in CH... | 28105274 |
| Free fatty acid receptor 4 | EC50 | = | 220.0 | nM | 6.66 | Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed... | 28105274 |
| Free fatty acid receptor 4 | EC50 | = | 878.0 | nM | 6.06 | FLIPR Assay: On the day before the measurement day, CHO cells expressing human G... | - |
| Free fatty acid receptor 1 | EC50 | = | 6300.0 | nM | 5.2 | Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction ... | 28105274 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28105274 | 10.1021/acsmedchemlett.6b00360 | Free fatty acid receptor 4 | 4 |
| 28105274 | 10.1021/acsmedchemlett.6b00360 | Free fatty acid receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine