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Compound Detail

CHEMBL3922001

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Cc1cccc(-c2c(O)cc(C(C)(C)c3ccccc3)cc2O)c1

Basic Information

ChEMBL ID CHEMBL3922001
Phase Preclinical
Structure Type MOL
InChI Key ARNITDLNJQTLMC-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

318.4
MW (Da)
5.40
ALogP
2
HBA
2
HBD
40.5
PSA (Ų)
0.68
QED
1
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H22O2
MW 318.42
Aromatic Rings 3
Heavy Atoms 24
NP-Likeness -0.16

Activity Summary

Ki 2 meas. best 8.64

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cannabinoid receptor 2
CHEMBL253
Ki 8.64 8.64 2.3 1
Cannabinoid receptor 1
CHEMBL218
Ki 7.33 7.33 46.7 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine