Compound Detail
CHEMBL392895
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CN(NS(C)(=O)=O)c1ncnc2c1ncn2[C@@H]1O[C@@H]2OP(=O)(OCOC(=O)C(C)(C)C)O[C@H]2[C@@]1(C)O
Basic Information
| ChEMBL ID | CHEMBL392895 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HVSLVYRUYWVEQM-SFZGVMPDSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
550.5
MW (Da)
0.42
ALogP
15
HBA
2
HBD
193.5
PSA (Ų)
0.21
QED
2
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 6.38 | 6.38 | 414.0 | 1 |
| Bovine viral diarrhea virus 1 CHEMBL612571 | EC50 | 6.02 | 6.02 | 962.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 414.0 | nM | 6.38 | Antiviral activity against hepatitis C virus replication | 17331721 |
| Bovine viral diarrhea virus 1 | EC50 | = | 962.0 | nM | 6.02 | Antiviral activity against Bovine viral diarrhea virus 1 | 17331721 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17331721 | 10.1016/j.bmcl.2007.02.030 | Hepatitis C virus | 1 |
| 17331721 | 10.1016/j.bmcl.2007.02.030 | Bovine viral diarrhea virus 1 | 1 |
Data from ChEMBL 36 via Core Engine