Assay Detail
Functional
CHEMBL891973
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Bovine viral diarrhea virus 1
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bovine viral diarrhea virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Bovine viral diarrhea virus 1 (CHEMBL612571) ↗| Type | ORGANISM |
| Organism | Bovine viral diarrhea virus 1 |
Publication
Cyclic monophosphate prodrugs of base-modified 2'-C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 6.82 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL234899 | — | — | 1 | 7.80 |
| CHEMBL233207 | — | — | 1 | 7.48 |
| CHEMBL397573 | — | — | 1 | 6.96 |
| CHEMBL234445 | — | — | 1 | 6.67 |
| CHEMBL392305 | — | — | 1 | 6.65 |
| CHEMBL234444 | — | — | 1 | 6.61 |
| CHEMBL234251 | — | — | 1 | 6.38 |
| CHEMBL392895 | — | — | 1 | 6.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL234899 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL233207 | — | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL397573 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL234445 | — | EC50 | = | 216.0 | nM | 6.67 |
| CHEMBL392305 | — | EC50 | = | 223.0 | nM | 6.65 |
| CHEMBL234444 | — | EC50 | = | 245.0 | nM | 6.61 |
| CHEMBL234251 | — | EC50 | = | 420.0 | nM | 6.38 |
| CHEMBL392895 | — | EC50 | = | 962.0 | nM | 6.02 |