Compound Detail
CHEMBL394592
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL394592 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BZSXHZSFVATPJB-KCJUWKMLSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
309.7
MW (Da)
1.25
ALogP
4
HBA
1
HBD
84.6
PSA (Ų)
0.79
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.0
Ki 1 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL1871 | EC50 | 9.0 | 9.0 | 1.0 | 1 |
| Androgen receptor CHEMBL1871 | Ki | 8.52 | 8.52 | 3.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | EC50 | = | 1.0 | nM | 9.0 | Agonist activity at human AR | 17292608 |
| Androgen receptor | Ki | = | 3.0 | nM | 8.52 | Binding affinity to human AR | 17292608 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17292608 | 10.1016/j.bmcl.2007.01.076 | Androgen receptor | 2 |
Data from ChEMBL 36 via Core Engine