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Compound Detail

CHEMBL3957163

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O=c1ccc2ccccc2n1CCCCCN1CCN(c2cccc3sccc23)CC1

Basic Information

ChEMBL ID CHEMBL3957163
Phase Preclinical
Structure Type MOL
InChI Key QRSVODFJOPEHOT-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

431.6
MW (Da)
5.21
ALogP
5
HBA
0
HBD
28.5
PSA (Ų)
0.38
QED
1
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H29N3OS
MW 431.61
Aromatic Rings 4
Heavy Atoms 31
NP-Likeness -1.53

Activity Summary

Ki 1 meas. best 8.59

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
5-hydroxytryptamine receptor 2A
CHEMBL322
Ki 8.59 8.59 2.6 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine