Compound Detail
CHEMBL397831
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC1=O
Basic Information
| ChEMBL ID | CHEMBL397831 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | JCBCIARBMHQADT-ROPOSLPCSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
1483.7
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prothrombin CHEMBL4471 | Ki | 4.39 | 4.39 | 40400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prothrombin | Ki | = | 40400.0 | nM | 4.39 | Inhibition of bovine thrombin | 17985858 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17985858 | 10.1021/jm0704898 | Suppressor of tumorigenicity 14 protein | 1 |
| 17985858 | 10.1021/jm0704898 | Prothrombin | 1 |
| 17985858 | 10.1021/jm0704898 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine