Compound Detail
CHEMBL3990514
LEVOXADROL 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL3990514 |
| Name | LEVOXADROL |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | HGKAMARNFGKMLC-MOPGFXCFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
1
Known Names
Molecular Properties
309.4
MW (Da)
3.45
ALogP
3
HBA
1
HBD
30.5
PSA (Ų)
0.94
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Single Enantiomer |
Activity Summary
Ki 1 meas. best 4.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 4.91 | 4.91 | 12300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 12300.0 | nM | 4.91 | Displacement of [3H]TCP from tissue homogenate preparation of whole rat brain mi... | 2903930 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2903930 | 10.1021/jm00120a004 | Glutamate NMDA receptor | 1 |
Data from ChEMBL 36 via Core Engine