Compound Detail
CHEMBL401313
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL401313 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZNSWMXKHYJKZDL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
450.5
MW (Da)
5.67
ALogP
4
HBA
1
HBD
63.1
PSA (Ų)
0.38
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| N-formyl peptide receptor 2 CHEMBL4227 | EC50 | 5.57 | 5.57 | 2710.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| N-formyl peptide receptor 2 | EC50 | = | 2710.0 | nM | 5.57 | Agonist activity at human recombinant FPRL1 expressed in CHO cells assessed as c... | 17920884 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17920884 | 10.1016/j.bmcl.2007.09.043 | N-formyl peptide receptor 2 | 1 |
| 17920884 | 10.1016/j.bmcl.2007.09.043 | fMet-Leu-Phe receptor | 1 |
| 20870313 | 10.1016/j.ejmech.2010.09.001 | N-formyl peptide receptor 2 | 1 |
Data from ChEMBL 36 via Core Engine