Compound Detail
CHEMBL403157
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL403157 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LHKAUBTWBDZARW-STHAYSLISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
101.1
MW (Da)
-0.58
ALogP
2
HBA
2
HBD
63.3
PSA (Ų)
0.46
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Gamma-aminobutyric acid receptor subunit rho-1 CHEMBL3561 | EC50 | 4.4 | 4.4 | 40000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Gamma-aminobutyric acid receptor subunit rho-1 | EC50 | = | 40000.0 | nM | 4.4 | Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus l... | 17981464 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17981464 | 10.1016/j.bmcl.2007.10.019 | Gamma-aminobutyric acid receptor subunit rho-1 | 1 |
Data from ChEMBL 36 via Core Engine