Compound Detail
CHEMBL403741
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Basic Information
| ChEMBL ID | CHEMBL403741 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CBCKQZAAMUWICA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
108.1
MW (Da)
0.85
ALogP
2
HBA
2
HBD
52.0
PSA (Ų)
0.48
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.06
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HT-22 CHEMBL614316 | EC50 | 6.06 | 6.06 | 879.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HT-22 | EC50 | = | 879.0 | nM | 6.06 | Neuroprotective activity in mouse HT22 cells assessed as protection against glut... | 24602904 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| 17827020 | 10.1016/j.bmc.2007.07.050 | Skin | 1 |
| 19465932 | 10.1038/nchembio.179 | Mus musculus | 1 |
| 24602904 | 10.1016/j.bmcl.2014.02.006 | HT-22 | 1 |
Data from ChEMBL 36 via Core Engine