Compound Detail

CHEMBL408983

TEPROTIDE

🧪 Phase II

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🧪 Phase II

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL408983
Name	TEPROTIDE
Phase	Phase II
Structure Type	BOTH
InChI Key	UUUHXMGGBIUAPW-CSCXCSGISA-N

Known Names

SO 20881 SO-20881 SQ 20881 SQ-20881 Tepromide Teprotida Teprotide

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

Molecular Properties

1101.3

MW (Da)

Drug Information

Molecule Type	Protein
Chirality	Single Enantiomer

Flags

Natural Product

USAN Stem	-tide
USAN Year	1976

Extended Properties

Molecular Formula	C53H76N14O12
MW	1101.28

Activity Summary

IC50 1 meas. best 6.66

Target Activity Profile

Target	Type	Best pChEMBL	Mean pChEMBL	Best (nM)	# Data
Angiotensin-converting enzyme CHEMBL1808	IC50	6.66	6.66	220.0	1

Activity Data Samples

Top measurements by pChEMBL value

Target	Type	Rel.	Value	Units	pChEMBL	Assay	PubMed
Angiotensin-converting enzyme	IC50	=	220.0	nM	6.66	Compound is evaluated for the inhibition of porcine plasma Angiotensin I convert...	6256550

Literature References

PubMed	DOI	Target Context	# Activities
6256550	10.1021/jm00186a020	Angiotensin-converting enzyme	1
2831364	10.1021/jm00398a012	Angiotensin-converting enzyme	1

Data from ChEMBL 36 via Core Engine