Compound Detail
CHEMBL41078
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL41078 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IGFJTSGNIPPHTD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
500.8
MW (Da)
5.17
ALogP
5
HBA
3
HBD
99.5
PSA (Ų)
0.43
QED
2
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily KQT member 2 CHEMBL2985 | EC50 | 6.18 | 6.18 | 663.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily KQT member 2 | EC50 | = | 663.0 | nM | 6.18 | Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in... | 15026035 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15026035 | 10.1016/j.bmcl.2004.01.073 | Potassium voltage-gated channel subfamily KQT member 2 | 4 |
Data from ChEMBL 36 via Core Engine