Potassium voltage-gated channel subfamily KQT member 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9Z351. Use UniProt Q9Z351 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Z351 as the stable identity anchor, then attach disease evidence before program review.
Potassium voltage-gated channel subfamily KQT member 2
Review this target as Potassium voltage-gated channel subfamily KQT member 2, mapped to UniProt Q9Z351. Sequence length is 759 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium voltage-gated channel subfamily KQT member 2 as ChEMBL target CHEMBL2985, mapped to UniProt Q9Z351. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Potassium voltage-gated channel subfamily KQT member 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9Z351 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium voltage-gated channel subfamily KQT member 2 |
| UniProt Accession | Q9Z351 |
| Component Type | Protein |
| Sequence Length | 759 aa |
Potassium voltage-gated channel subfamily KQT member 2
Review this target as Potassium voltage-gated channel subfamily KQT member 2, mapped to UniProt Q9Z351. Sequence length is 759 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2440363 | 9.05 | EC50 | 0.9 | Preclinical |
| CHEMBL401942 | 8.62 | EC50 | 2.4 | Preclinical |
| CHEMBL361184 | 8.0 | EC50 | 10.0 | Preclinical |
| CHEMBL180886 | 7.7 | EC50 | 20.0 | Preclinical |
| CHEMBL176931 | 7.22 | EC50 | 60.0 | Preclinical |
| CHEMBL179854 | 6.92 | EC50 | 120.0 | Preclinical |
| CHEMBL174891 | 6.7 | EC50 | 200.0 | Preclinical |
| CHEMBL182734 | 6.48 | EC50 | 330.0 | Preclinical |
| CHEMBL183908 | 6.43 | EC50 | 370.0 | Preclinical |
| CHEMBL41078 | 6.18 | EC50 | 663.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 14 | 6.4 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 7 | 7.4 |