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Compound Detail

CHEMBL4114761

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CCC/C(C(=O)O)=C1\O[C@@H]2CC(=O)N2C1C(=O)O

Basic Information

ChEMBL ID CHEMBL4114761
Phase Preclinical
Structure Type MOL
InChI Key QAABSWVJCGWPMP-SKQQWWGDSA-N
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

255.2
MW (Da)
0.17
ALogP
4
HBA
2
HBD
104.1
PSA (Ų)
0.55
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H13NO6
MW 255.23
Aromatic Rings 0
Heavy Atoms 18
NP-Likeness 1.15

Activity Summary

IC50 3 meas. best 6.59

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-lactamase TEM
CHEMBL2364670
IC50 6.59 6.59 254.0 1
Beta-lactamase SHV-1
CHEMBL5956
IC50 6.36 6.36 435.7 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine