Compound Detail
CHEMBL41226
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Basic Information
| ChEMBL ID | CHEMBL41226 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FCGZRGKHRSLYNZ-ZKWNWVNESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
397.6
MW (Da)
7.38
ALogP
2
HBA
0
HBD
33.5
PSA (Ų)
0.22
QED
1
Ro5 Violations
16
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL3229 | IC50 | 4.62 | 4.62 | 24000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 24000.0 | nM | 4.62 | Maximum Inhibition of fatty acid amide hydrolase (FAAH) was determined using rat... | 12672252 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12672252 | 10.1021/jm0210818 | Homo sapiens | 2 |
| 12672252 | 10.1021/jm0210818 | Fatty-acid amide hydrolase 1 | 2 |
| 12672252 | 10.1021/jm0210818 | Cannabinoid receptor 1 | 1 |
| 12672252 | 10.1021/jm0210818 | Cannabinoid receptor 2 | 1 |
| 12672252 | 10.1021/jm0210818 | Transient receptor potential cation channel subfamily V member 1 | 1 |
Data from ChEMBL 36 via Core Engine