Compound Detail
CHEMBL4167006
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4167006 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RCFSZDOVSFYAFR-RVDMUPIBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
295.3
MW (Da)
3.39
ALogP
5
HBA
1
HBD
97.7
PSA (Ų)
0.31
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma cruzi CHEMBL368 | IC50 | 5.09 | 5.09 | 8070.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma cruzi | IC50 | = | 8070.0 | nM | 5.09 | Antitrypanosomal activity against Trypanosoma cruzi Colombiana Tc1 epimastigotes... | 29247858 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29247858 | 10.1016/j.ejmech.2017.12.011 | Trypanosoma cruzi | 3 |
Data from ChEMBL 36 via Core Engine